What are atypical antidepressant drugs?

An atypical antidepressant is any antidepressant medication that acts in a manner that is different from that of most other antidepressants. Atypical antidepressants include agomelatine, bupropion, mianserin, mirtazapine, nefazodone, opipramol, tianeptine, and trazodone.

What is unique about atypical antidepressants?

Atypical antidepressants ease depression by affecting chemical messengers (neurotransmitters) used to communicate between brain cells.

When are atypical antidepressants prescribed?

Atypical antidepressants are frequently used in patients with major depression who have inadequate responses or intolerable side effects during first-line treatment with SSRIs [2].

Why is bupropion an atypical antidepressant?

When introduced in the United States in 1989, bupropion was categorized as an “atypical” antidepressant because its neurotransmitter effects were undefined but known to differ from those of classical antidepressants (tricyclic antidepressants [TCAs] and monoamine oxidase inhibitors [MAOIs]) and selective serotonin …

What is atypical medication?

The term “atypical” refers to an antipsychotic medication that produces minimal extrapyramidal side effects (EPS) at clinically effective antipsychotic doses, has a low propensity to cause tardive dyskinesia (TD) with long-term treatment, and treats both positive and negative signs and symptoms of schizophrenia [1].

Why are atypical antidepressants prescribed?

What is the cheapest antidepressant?

Citalopram (Celexa) is an inexpensive drug used to treat depression. It is slightly less popular than comparable drugs. This drug is available in generic and brand versions. Generic citalopram is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may lower.

Are atypical antidepressants safe?

Atypical antidepressants are safe for most people. However, in some circumstances they can cause problems. For example: Bupropion should not be used by people who have a seizure disorder or an eating disorder such as bulimia or anorexia.

Which is the best atypical antidepressant for depression?

Atypical antidepressants approved by the FDA. The Food and Drug Administration (FDA) approved these atypical antidepressants to treat depression: Bupropion (Wellbutrin SR, Wellbutrin XL, others) Mirtazapine (Remeron) Nefazodone. Trazodone. Vilazodone (Viibryd) Vortioxetine (Trintellix)

Are there any side effects to taking atypical antidepressants?

Possible side effects of atypical antidepressants. Some antidepressants may cause constipation, while others may increase the risk of diarrhea. Some antidepressants may increase your appetite, resulting in weight gain, while others may cause nausea. Some antidepressants are less likely than others to cause sexual side effects.

What is the mechanism of action of an atypical antidepressant?

Atypical antidepressants are medications that have the ability to alleviate or eliminate symptoms of depression but do so in a way that is unlike the mechanisms of action seen in common antidepressants.

How are tricyclic antidepressants responsible for their tolerability?

Tricyclic antidepressants have multiple sites of pharmacological actions which are responsible for their tolerability and toxicological problems as well as their efficacy. That fact has prompted the search for antidepressants with fewer sites of action.