Which medication is a first-generation antihistamine?

Diphenhydramine (Benadryl, Aler-Dryl, Allergy Relief, Banophen, Diphen, Genahist, Ormir) Common first-generation agent available OTC in the United States.

What is the best first-generation antihistamine?

Diphenhydramine is a first-generation H1-antihistamine, a class of drugs that works by binding and stabilizing the H1-histamine receptor. It is found in a variety of allergy, cold, and sleep medications, with Benadryl as the best-known product.

What are first and second generation antihistamines?

First-generation antihistamines block both histaminic and muscarinic receptors as well as passing the blood-brain barrier. Second-generation antihistamines mainly block histaminic receptors and do not pass the blood-brain barrier.

Which drug is used as an antihistamine?

First Generation Antihistamines

What is the most effective over the counter antihistamine?

Best Overall: Allegra Adult Non-Drowsy Antihistamine Tablets

• Provides relief within an hour.
• Non-drowsy unlike other antihistamines.
• Soothes both indoor and outdoor allergies.

Which second generation antihistamine is best?

However, among the antihistamines presently available, fexofenadine may offer the best overall balance of effectiveness and safety, and this agent is an appropriate selection for initial or switch therapy for most patients with mild or moderate allergic symptoms.

What is the fastest acting allergy medicine?

BENADRYL® Allergy Relief is the fastest-acting allergy relief capsule, it is the only brand to contain acrivastine a unique active ingredient. Acrivastine starts to work in 15 minutes providing fast relief. It can also be taken as required (up to three times per day) so that you can take as and when you need.

What is the best non-drowsy antihistamine?

Based on consumer reviews, Alavert 24-Hour Non-Drowsy Allergy Relief is the best non drowsy allergy medicine available today. Containing 10mg of loratadine per tablet, this synthetic antihistamine has been developed to provide 24 hour of lasting relief against the symptoms of allergies.

How safe are second generation antihistamines?

The second-generation antihistamines do not cross the blood-brain barrier to the extent that first-generation do and therefore do not cause drowsiness at standard dosage levels. Second-generation antihistamines are considered to be safer than first generation antihistamines because they don’t cause drowsiness and interact with fewer drugs.

What over-the-counter antihistamines are available?

Brompheniramine (brand names include Children’s Dimetapp Cold)

What do about third generation antihistamines?

and nose or throat itching from hay fever and other upper