Is exenatide the same as bydureon?

Bydureon is only available as a brand-name medication. It’s not available in a generic form. Bydureon contains extended-release exenatide. A regular-release form of exenatide is available as the brand-name drug Byetta.

What is exenatide microspheres used for?

Exenatide is used either alone or with other medications, and with a proper diet and exercise program, to control high blood sugar in people with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems.

Is exenatide subcutaneous?

Exenatide (Subcutaneous Route)

Where is exenatide administered?

Exenatide can be administered in the thigh (upper leg), abdomen (stomach), or upper arm. Use a different site for each injection, about 1 inch (2.5 centimeters) away from the previous injection but in the same general area (for example, the thigh).

Why was Bydureon discontinued?

On September 14, 2020, AstraZeneca announced that Bydureon (exenatide) Pen will be discontinued as of March 2021 due to business reasons. — The discontinuation is not due to safety or efficacy issues, product quality or manufacturing concerns. Bydureon BCise® (exenatide) Pen will continue to be available.

What are the side effects of exenatide?

Nausea, vomiting, diarrhea, nervousness, or upset stomach may occur as your body adjusts to the medication. Nausea usually lessens as you continue to use exenatide. Other side effects include decreased appetite or weight loss. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Does exenatide cause pancreatitis?

Analyses of large claims and pharmacy databases have shown no apparent increased risk for pancreatitis in patients taking exenatide,7–9 while a concern over the possibility of an increased risk of pancreatic cancer from exenatide use has been raised in the FDA adverse event reporting system (AERS) database.

What are the side effects of bydureon pen?

COMMON side effects

• indigestion.
• constipation.
• weight loss.
• headache.
• nausea.
• vomiting.
• diarrhea.

When should I start exenatide?

The best way to achieve this is to have your first injection during the hour before your first meal of the day, and the second injection during the hour before your evening meal. If you forget to use exenatide before a meal, do not inject it after you have eaten, but instead just wait until your next dose is due.

How long is the half life of exenatide?

Exenatide is administered subcutaneously and mimics human glucagon-like peptide-1 (GLP-1). Compared to GLP-1, exenatide has a longer half-life of 2.4 hours. Exenatide is a GLP-1 Receptor Agonist. The mechanism of action of exenatide is as a Glucagon-like Peptide-1 (GLP-1) Agonist.

When is the best time to inject exenatide?

Exenatide extended-release (long-acting) (Bydureon ®) comes as a powder to be mixed with liquid in a vial or a prefilled dosing pen to inject subcutaneously. Exenatide immediate-release solution is usually injected twice a day within 60 minutes before the morning and evening meals; do not inject it after meals.

What are the side effects of an exenatide injection?

If so, your doctor will probably tell you not to use exenatide injection. If you experience any of the following symptoms, call your doctor immediately: a lump or swelling in the neck; hoarseness; difficulty swallowing; or shortness of breath. Keep all appointments with your doctor and the laboratory.

What kind of pen do you use to inject exenatide?

Exenatide immediate-release (Byetta®) comes as a solution (liquid) in a prefilled dosing pen to inject subcutaneously (under the skin). Exenatide extended-release (long-acting) (Bydureon®) comes as a powder to be mixed with liquid in a vial or a prefilled dosing pen to inject subcutaneously.