What does IgA deficiency cause?

Some people with an IgA deficiency are more likely to get frequent infections. These can include sinus, lung, and digestive infections. Some people with IgA deficiency also are more likely to have allergies, and digestive and autoimmune problems such as celiac disease or lupus.

Does IgA deficiency predispose to respiratory infections?

Respiratory infections and autoimmune disease are more common in IgA-deficient patients. A few patients with IgA deficiency presenting in childhood may recover spontaneously; other patients may develop CVID.

Which is the most common selective immunoglobulin deficiency?

Immunoglobulin A (IgA) deficiency is the most common primary immunodeficiency defined as decreased serum level of IgA in the presence of normal levels of other immunoglobulin isotypes. Most individuals with IgA deficiency are asymptomatic and identified coincidentally.

What is partial IgA deficiency?

Partial IgA deficiency refers to serum levels above 7 mg/dL but below the lower limit of normal (ie, lower than 2 standard deviations below the age-adjusted mean).

How can I increase my IgA naturally?

High IgA Levels? 5 Ways to Improve Immune Health

1. 1) Cocoa.
2. 2) Avoiding Alcohol.
3. 3) Sexual Activity in Women.
4. 4) Anger Management.
5. 5) Refraining from Fasting.
6. Estrogen Levels.
7. Learn More.

What drugs can cause IgA deficiency?

Drugs known to cause IgA deficiency include:

• Sulfasalazine.
• D penicillamine.
• Gold.
• Phenytoin, valproic acid.
• Thyroxine.
• Captopril.
• Levamisole.
• Cyclosporine.

What is normal range for IgA test?

The IgA normal range differs with age and the IgA normal range for an healthy adult is between 80 – 350 mg/dL.

Does IgA decrease with age?

Salivary and serum immunoglobulins were quantified by enzyme-linked immunosorbent capture assays. The levels of serum immunoglobulin G (IgG) and IgM were significantly reduced in the oldest age group, whereas no significant reduction in the level of IgA with age was observed.

What is IgA test done for?

Doctors may order an IgA test to diagnose problems with the immune system, intestines, and kidneys. They’re also done for kids who have recurrent infections.

What are the side effects of selective IgA deficiency?

A common problem in Selective IgA Deficiency is susceptibility to infections. This is seen in about half of the patients with IgA deficiency that come to medical attention. Recurrent ear infections, sinusitis, bronchitis and pneumonia are the most common infections seen in patients with Selective IgA Deficiency.

What are some autoimmune diseases that can be caused by IgA deficiency?

Autoimmune diseases, in which your immune system attacks particular organs or tissues in your own body, can be found with Selective IgA deficiency. Common autoimmune conditions found with IgA deficiency include rheumatoid arthritis and lupus.

Is there a Facebook group for selective IgA deficiency?

Join Selective IgA Deficiency: An Official IDF Facebook Group. Selective IgA Deficiency is one of the most common primary immunodeficiency diseases. Studies have indicated that as many as one in every 500 Caucasian people has Selective IgA Deficiency.

What’s the difference between IgA and secretory IgA?

Secretory IgA has some differences compared to the IgA present in the blood. Secretory IgA is made of two IgA antibody molecules joined together by a protein called the J chain (“J” for “joining”).